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The rule of thumb that four half-lives must elapse after starting a drug-dosing regimen before full effects will be seen is based on the approach of the accumulation curve to over 90% of the final steady-state concentration

The expression levels were compared between treated and control groups [2]

If you have only mild symptoms of B12 deficiency, you should notice the effects of treatment relatively quickly

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7Ashows immunohistochemistry images of hair cells with nuclei stained in blue (DAPI) and hair cells stained with myosin VIIA ingreen following0 M of cisplatin (first image from left), 10 M of cisplatin for 48 hours (second image from left), 50 M of cisplatin for 48 hours (third image from left), and 10 M of cisplatin for 72 hours (fourth image from left).FIG