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This minimizes confusion and also clarifies that no matter which of these substances are abused, the withdrawal symptoms are the same as well as treatment options.[1] What is the Difference Between Opiates and Opioids

Estimated prevalence of Alzheimer's disease across the entire cognitive spectrum Finally, as measurements of the brain changes of Alzheimer's disease become more widely available in research, we will be able to estimate how many people have Alzheimer's disease regardless of the presence or absence of dementia or any form of cognitive impairment

While the applicant states that SPEVIGO will be the first GPP treatment targeting the IL-36 pathway, we note that per the applicant, other treatments are available and we therefore question whether placebo is the most appropriate comparator

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doi:10.3390/ijerph7041342