The terminal half-life was determined based on the terminal slope, which was obtained by converting the micro-constants from the 2-compartment model to macro constants ( 03hr ) was obtained by integrating the curve over this time period, while the total AUC (AUC 0- ) was derived using the dose divided by clearance
Chez MG, Chang M, Krasne V, Coughlan C, Kominsky M, Schwartz A
As expected, rotenone increased the production of ROS in both cell lines, but probably due to different expression of efflux pumps and therefore uncertainties in the assay (Sieprath et al
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