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doi: 10.1210/er.2006-0021

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A century ago, three-quarters of prescriptions required some sort of in-pharmacy compoundingmixing up drug formulations in the shop rather than giving a patient a standard off-the-shelf medicationbut that number dropped to 1% by the 1970s

The only way absorption can occur in the blood stream is when the right amounts of both B12 and intrinsic factor are present

Ethics declarations Competing interests SJW is the founder of Ridgeline Therapeutics, HN is a paid employee of Ridgeline Therapeutics and, since manuscript submission, ADW has also become a paid employee of Ridgeline Therapeutics