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However, the addition of exogenous GSH reduced activities of the PA synthesis-enzymes like arginine decarboxylase (ADC), S-adenosylmethionine decarboxylase (SAMDC), and diamine oxidase (DAO), while increased the activities of polyamine oxidase (PAO) and ornithine decarboxylase (ODC), resulting in reduced levels of PAs such as Spd, Spm and Put

While mitochondria produce ROS during oxidative phosphorylation, the ROS are appropriately eliminated by several antioxidants under normal physiological conditions

consume enough Vitamin B12, there are tell-tale signs you might have a deficiency

Otherwise, you will need to monitor your condition carefully and consult a specialist regularly

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