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The most extreme cognitive effect of developmental iodine deficiency is irreversible mental retardation

Also, a substantial decrease in glutathione levels precedes the mitochondrial dysfunction and neuronal death found in Parkinsons disease, suggesting GSH depletion may initiate the subsequent impairment.It also suggests that increasing GSH levels may have potential benefit toward preventing diseases associated with mitochondrial dysfunction

The British Journal of Nutrition

Pierce, A

It is specifically characterized by inflammation, demyelination, and neuronal loss and manifests with a range of neurological symptoms including numbness, tingling, vision impairment, cognitive impairment, and bladder and bowel dysfunction (Tafti et al., 2024)