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By integrating mechanistic evidence, biomarker discoveries, and emerging data from human studies, it will be examined how chronic circadian disruption may drive breast carcinogenesis, how novel molecular tools could refine individual risk stratification, and, finally, how these insights might reshape regulatory frameworks and preventive strategies 17

Subsequent de-hydroxylation reactions generate urolithins with varying degrees of hydroxylation, with urolithin A being a dihydroxy urolithin (20, 27)

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doi: 10.1016/j.chom.2023.03.020 74 QiuP.IshimotoT.FuL.ZhangJ.ZhangZ.LiuY

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