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Adams GE, Armstrong RC, Charlesby A et al (1969) Pulse radiolysis of sulphur compounds

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LPS activates macrophages through TLR 4, prompting the release of inflammatory factors such as IL-1 and TNF- , which drive Th 1 differentiation and promote IFN- secretion, further magnifying local inflammation in the thyroid gland (Zhang et al., 2023)

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5,10-Methylene tetrahydrofolate (THF) is required for the synthesis of nucleic acids and is reduced to 5-methyl THF by methylene THF reductase, a flavin-dependent enzyme that uses NADPH as a cofactor