Sublingual administration, which bypasses the gastrointestinal tract, appears to be equally effective as IM injections while being less invasive and more cost-efficientparticularly in patients with atrophic gastritis, post-gastrectomy status, or conditions that impair intrinsic factor-mediated absorption, where long-term intervention is often required
This represents a significant limitation in the evidence base, as large-scale human trials examining musculoskeletal applications have not been published
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Sikiric, P., Seiwerth, S., Ruman, R., Turkovi, B., Rokotov, D., Bri, L., Sever, M., Klicek, R., Radi, B., Drmic, D., Ili, S., Kolenc, D., Stambolija, V., Zorii, Z., Vri, H., & ebei, B
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