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Anti-inflammatory approaches, such as the IL-1 inhibitor canakinumab in the CANTOS trial, have also been used to reduce cardiovascular events (117)

Herein, the equal number of cells were incubated with 100 g/mL of selected flavonoids against positive control, lysed, and examined on the zymogram

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If side effects emerge (injection site reactions, unusual symptoms), reduce dosage or frequency

After SARS-CoV-2 infection, the viremia stage could increase OxS, elevated levels of ROS/inflammation markers (i.e., peroxide, NO, carbonylated proteins, and IL-6) and inflict severe cellular/tissue damage