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(Outlines contraindications for niacin therapy, including active peptic ulcer disease, active liver disease with elevated enzymes, hypersensitivity to niacin, and arterial bleeding, as well as monitoring recommendations for blood pressure, glucose, uric acid, etc., due to niacins systemic effects)

Protective effects of bee venom-derived phospholipase A2 against cholestatic liver disease in mice

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After evaluating the peptide on aged cell cultures, the researchers apparently observed reduced senescence-associated staining and lower protein levels of p16, p21, and p53 in the remaining cell population, consistent with the removal of cells that highly expressed these markers

Nausea (41%), diarrhea (23%), vomiting (20%), and constipation (18%) are the most frequently reported