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Because of its role in cellular function, some healthcare providers include glutathione as part of certain wellness or metabolic support plans

Future studies should incorporate mechanism-relevant biological markers, including serum BDNF to index neurotrophic signaling, inflammatory markers such as CRP and IL-6, measures of HPA-axis activity such as the cortisol awakening response, and neuroimaging markers (e.g., fMRI-based assessments of hippocampal connectivity), to more precisely characterize treatment response and patient stratification

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Given these mixed profiles, therapy during pregnancy should begin only after shared decision-making, using the lowest effective frequency, avoiding occlusion, and limiting treatment areas

It should be noted that compounds that stimulate the higher GSH efflux are not always the best to induce CS and conversely