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As a result, DES(1-3) IGF-1 exhibits roughly 10-fold greater potency than native IGF-1 in cell-based assays, despite identical IGF1R binding affinity the potency difference is entirely attributable to less sequestration

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10.2174/0115680266274272240321065039 32 CoassinM.ArrigoA.RicciF.RosaR.GattegnaR.PupinoA.et al (2023)

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