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Finally, in the case of drugs that induce (eg, carbamazepine) or inhibit (eg, fluoxetine) their own metabolism, 12,13 it is necessary to know what the half-life is at least 24 weeks after treatment initiation, when enzyme induction or inhibition reaches its peak

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This suggests that GLP-1R mice may serve as a model of correlated metabolic-functional connectivity changes in the brain