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This study aimed to provide a direct comparison with the current drinking water administration method and to address the mixing kinetics and solubility issues highlighted by Vervaet et al
Multiple cellular processes are considered to contribute to this functional decline and these are collectively referred to as the hallmarks of aging and these include processes like genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, disabled macroautophagy, deregulated nutrient-sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, altered intercellular communication, chronic inflammation, and dysbiosis 1
In mitochondria, a GSH intracellular transport system located on the inner mitochondrial membrane and that mediates the movement of GSH from the cytosol into the mitochondrial matrix was reported [106,107,123]
