In a 2020 review, the researchers corroborated that silymarin's capacity to reduce oxidative stress on the liver could indeed improve biomarkers associated with conditions such as alcoholic fatty liver disease, nonalcoholic fatty liver disease, alcoholic cirrhosis, and drug-induced liver injury.29 Although the studies covered in the review used 420mg silymarin doses, others have found that amounts as low as 200mg could also impart the desired effects on liver health.30 If that weren't all, a 2018 study concluded that silymarin may actually increase glutathione levels in the liver.31 Selenium (55mcg) Selenium is an essential mineral with antioxidant properties, and one that may increase levels of an enzyme called glutathione peroxidase (GPx).32 GPx is important because it uses reduced glutathione to neutralize hydrogen peroxide,33 one of the major ROS
Vitamin C also inhibits the enzyme tyrosinase and thus contributes to the decrease in melanin production
As aforementioned, green tea contains multiple compounds with antioxidant properties, the most important of which are catechins, or tea flavonoids
However, dexamethasone mitigates ovalbumen-induced eosinophilic airway inflammation, including airway hyperresponsiveness, leukocyte infiltration, goblet cell hyperplasia, Th2 cytokine production, and the expression of pyroptosis markers, by inhibiting the HIF-1-glycolysis-lactate axis and subsequent protein lactylation
Japan Glutathione Value 2021-2025 ($ Millions) Figure 120
