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Knockout mutants for cytosolic NADP-isocitrate dehydrogenase (At1g65930) do not show a significant difference in whole leaf NADP + :NADPH ratios, but the absence of this enzyme does modify the GSH:GSSG ratiounder conditions of increased H 2 O 2 availability (Mhamdi et al., 2010b)

Dosage should be adjusted flexibly according to the purpose of use, following the principle of gradual increment

Therefore, in our transcriptomic analysis, special interests were paid to pathways of carbon metabolism, lipid metabolism (glycerophospholipid) and DNA biosynthesis (including cell cycle, DNA replication and purine/pyrimidine metabolism)

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