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The ability of hydroxocobalamin to rapidly scavenge and detoxify cyanide by chelation has resulted in several acute animal and human studies using systemic hydroxocobalamin doses at suprapharmacological doses as high as 140 mg/kg to support its use as an intravenous (IV) treatment for cyanide exposure

Variable Bioavailability: Oral dosing may result in inconsistent absorption, affecting effectiveness or tolerability

Cyanotoxin contamination in commercial Spirulina food supplements

Hum Gene Ther 2017;28:111821

Glutathione peroxidase 3 Glutathione peroxidase 3 (GPx-3), also known as plasma glutathione peroxidase (GPx-P) or extracellular glutathione peroxidase is an enzyme that in humans is encoded by the GPX3 gene