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In a subsequent analysis of data from this trial, the septic patients that were given parenteral thiamin (n=31) had lower creatinine concentrations throughout the treatment and were less likely to need renal replacement therapy compared to placebo (n=39

Disadvantages: Must be handled with dry hands, cannot be split or crushed, must remain in original packaging until use, limited dose flexibility

Zhao Y, Li M, Yao X, Fei Y, Lin Z, Li Z, et al

But for those noticing a consistent dip in energy or cognitive sharpness, B12 injections could be a game-changer

[DOI] [PMC free article] [PubMed] [Google Scholar] 801.Rommelaere S., Schpfer F., Armand F., Hamelin R., Lemaitre B