This action supports the cartilage repair process, aiming to regenerate and maintain healthy joint structure
[DOI] [PubMed] [Google Scholar] 25.Bach MA, Roberts CT, Jr, Smith EP, LeRoith D
In OA models induced by interleukin-1 beta (IL-1) and ferric ammonium citrate (FAC), hallmark ferroptosis markers such as glutathione peroxidase 4 (GPX4) and solute carrier family seven member 11 (SLC7A11) exhibit significant downregulation, whereas expression levels of the tumor suppressor gene p53 and acyl-CoA synthetase long-chain family member 4 (ACSL4) are elevated (Yao et al., 2021)
Additionally, Acetyl-L-carnitine , a dietary supplement, demonstrated potential in mitigating selenite-induced lens opacification when administered via intraperitoneal injection, reducing cataract incidence to 37.5% [62]
How Is Reduced Glutathione Administered