For example, biomineralized nanoparticles SBC@CaP derived from aging red blood cell vesicles and coated with pH-responsive calcium phosphate (CaP) shells, gradually dissolve the CaP layer in the acidic TME and expose the aging red blood cell membrane, enabling TAMs to selectively recognize and phagocytize them, achieving precise TAMs clearance, TME remodeling and immune activation thereby inhibiting tumor progression (55)
Both are overwhelmingly preclinical for recovery
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Cell culture and regents The Jurkat human T cells were obtained from the American Type Culture Collection (Manassas, VA, USA)
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