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Science 276:16991702, PMID: 9180080 Takaki J, Fujimori K, Miura M, Suzuki T, Sekino Y, Sato K (2012) l-glutamate released from activated microglia downregulates astrocytic l-glutamate transporter expression in neuroinflammation: the collusion hypothesis for increased extracellular l-glutamate concentration in neuroinflammation

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If you have cancer: In cancer, cysteine and glutathione may help tumor cells resist some types of chemotherapy.[ref] Talk to your oncologist or doctor about whether NAC or anything that boosts glutathione is a good idea for you