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Barrier dysfunction is documented and accepted in conditions such as celiac disease and Crohn's disease , and the phenomenon has been studied since the 1970s

The rationale for this combination was further recommended on account of rapid relief of symptoms by the 1 -AR antagonists, without targeting the underlying disease process along with mid or more sustained relief of symptoms by the 5ARIs [94]

His publications are included here for their relevance to BPC-157 research literature and controlled interpretation, not as commercial product support

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