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Trace elements in human physiology and pathology

They exist in a regulatory gray area, available for research purposes but not sanctioned for medical treatment

Additional risk factors include: Chronic kidney disease : Reduced renal clearance may impair B12 excretion Liver disease : Hepatic dysfunction can disrupt B12 metabolism and storage Myeloproliferative disorders : Certain blood cancers increase B12-binding proteins Concurrent medication use : Some drugs may interact with B12 metabolism, including metformin, proton pump inhibitors, and H2 antagonists Patients with these conditions should have B12 supplementation carefully monitored by their healthcare team

Consistent use for 8-12 weeks is typically recommended

But youll find that theres a lot of sensationalism and sometimes, theres perverse incentives that motivate people.And so you can get a sensationalistic story that makes headlines, and just everyone becomes aware of it