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Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress

When the body lacks this vital vitamin, several symptoms can occur: Common Symptoms: Fatigue and weakness Tingling or numbness in hands and feet Memory issues Mood swings or depression Loss of appetite Common Causes: Vegetarian or vegan diet (B12 is mostly found in animal-based foods) Poor gut absorption Long-term use of certain medications (e.g., metformin, antacids) Aging What Happens If Left Untreated

Reduced Inflammation Inflammation is at the root of many chronic health issues, from arthritis to heart disease

doi:10.1016/0091-3057(81)90061-7 PMID: 6895670 6

Mechanistic Insights into Hyperuricemia-Associated Renal Abnormalities with Special Emphasis on Epithelial-To-Mesenchymal Transition: Pathologic Implications and Putative Pharmacologic Targets