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The method of any one of embodiments 79-155, wherein the composition further comprises an excipient that increases the release rate of the therapeutic agent

The lack of FDA approval for human use and the need for higher doses in some experimental settings underscore the importance of evaluating safety and efficacy under strict medical supervision

Abstract Epitalon, a naturally occurring tetrapeptide, is known for its anti-aging effects on mammalian cells

Accordingly, diprenorphine is least soluble at slightly basic pH values, where neither group is ionized: increasing the pH beyond 9 results in deprotonation of the phenol, while decreasing the pH below 8 results in protonation of the amine (Figure 8)

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