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The DV for vitamin B12 is 6.0 mcg

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Thus, interference with mitochondrial metabolism may represent an effective strategy to enhance the activity of chemotherapeutic drugs in MNA-NB

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Samples were concentrated to dryness in vacuum before dissolving in 150 L 80% methanol solution, then centrifuged again at 13 500 g and 4C for 10 min, and the supernatant was transferred to a new tube for LC-MS detection