Csibi, A
CB-839 (Telaglenastat), a potent, reversible, and selective small-molecule inhibitor that targets GLS-1 and has a half-maximal inhibitory concentration (IC 50 ) of 24 nM for recombinant human glutaminase C, has been investigated in solid tumors and in AML, diffuse large B-cell lymphoma, and multiple myeloma cells alone or in combination with other anticancer drugs (10, 11, 2026)
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Proc Natl Acad Sci U S A 104(19):78577862 Parnham MJ (2011) Immunomodulatory approaches to the treatment of infections
Read 2 of the gene expression libraries was mapped to the reference genome (mouse mm10, v3.0.0) using STAR