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Genetics also determine skin melanin levels

[8] Melanotan II produces melanogenesis by activation of the MC 1 receptor, whereas its clinically documented sexual effects are thought to be related to its ability to activate the MC 4 receptor (though the MC 3 is thought to also possibly be involved)

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Fact: Even doses within the recommended range can significantly lower glutathione levels, especially if you have other stressors like poor sleep, alcohol intake, or a low-protein diet

The 100mg dose of phosphatidylserine may provide some benefit, and the 25mg of Sceletium tortuosum extract is in line with many studies