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After the initial treatment period, maintenance doses may be given less frequently

This is when individuals often feel confident that the treatment is working

If you eat very little meat, fish, eggs, or dairy or none at all dietary B12 is likely insufficient

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In the alkaline environment of the small intestine, R-proteins are degraded by pancreatic enzymes, freeing vitamin B 12 to bind to intrinsic factor (IF), a protein secreted by specialized cells in the stomach (parietal cells)