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5mg with 2mL = 2,500mcg/mL

In some embodiments, the formulations described herein have a pH and/or practical osmolarity as described herein, and have a concentration of active pharmaceutical ingredient from about 0.0001% to about 60%, from about 0.001% to about 40%, from about 0.01% to about 20%, from about 0.01% to about 10%, from about 0.01% to about 7.5%, from about 0.01% to about 6%, from about 0.01 to about 5%, from about 0.1 to about 10%, or from about 0.1 to about 6% of the active ingredient by weight of the formulation

References: Primary Withdrawal Study (107 patients): Dick P, Costa C, Fayolle K, Grandjean ME, Khoshbeen A, Tissot R

TB-500 Pharmacokinetics and Systemic Distribution TB-500 enters systemic circulation within 30 minutes of subcutaneous injection, reaching peak plasma concentration between 46 hours regardless of injection site or time of day

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