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The Challenge of Tendon and Ligament Healing Tendons and ligaments have notoriously poor blood supply, which is why these injuries often become chronic

Some individuals experience injection site reactions or sensitivity to components of the injection

P21-activated kinase 2 (PAK2) is a tamoxifen resistance inducer, while IGF1R can lead to the development of tamoxifen resistance by promoting the expression of PAK2 (Zhang et al., 2018)