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Materials and methods Cell culture Human ovarian cancer cell line (A2780 and its CDDP-resistant variant A2780DDP) and human colonic cancer cell line (HCT8 and its CDDP-resistant variant HCT8DDP) were donated by Dr K J Scanlon (Biochemical Pharmacology, City of Hope National Medical Center, Duarte, CA, USA)

In a cell line study, NAC has shown the potential to reduce the dysfunction of both dopamine and glutamate by enhancing dopamine receptor binding and neuronal viability (181)

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A., Jacks, P