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Dixon D, Edmonds M

The phase 3 trial is in 8,000+ patients with established cardiovascular disease and elevated Lp(a) with a hard primary endpoint composite of cardiovascular death, myocardial infarction, stroke, or urgent coronary revascularization requiring hospitalization

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[12] RxList

However, some studies have found increased GABA concentrations and GABA/creatine ratios in the left dorsolateral prefrontal cortex of adult ASD patients, which may support the excitation/inhibition (E/I) imbalance hypothesis, suggesting enhanced inhibitory function in this region (132, 133)