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10.1073/pnas.0702018104 27 NoveroA

He said naturally occurring peptides were kept within very particular levels by the body, meaning that increasing their levels via injections could throw its systems out of balance

Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans

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This is why in combination with carbohydrates, it allows you to preserve glycogen stores and utilize fatty acids as a source of energy