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Peripheral inflammatory mediators may also activate the vagus nerve to transmit signals to the central nervous system (Capuron and Miller, 2011)

Since it is suggested that p53, p16, p21 are directly related to the induction of senescence in chondrocytes (Ashraf et al., 2016), we thus used qRT-PCR and western blot analysis to examine their expression levels

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4 BioSpace (PR Newswire)Announcement on completion of the Phase 2b obesity trial of AOD-9604