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The cause of skin necrosis is tissue hypoxia or ischemia as well as bacterial infection

LeTrilling et al , 2018) due to the inability to interfere with STAT2dependent IFN signalling as evident from the restored replication in STAT2deficient mice (LeTrilling et al , 2018)

It was unexpected that the mice subjected to the transient increase in gut permeability were resistant to colitis induced by the administration of trinitrobenzene sulfonic acid

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