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This small panel of compounds demonstrates how specific structural variations can be readily tested for their potential ability to drive accumulation in E

Finally, a second regulatory region, the regulatory insertion (residues 615-643), interacts with the R-domain through an electrostatic or H-bond interaction from K617 to S903, another residue that is known to be phosphorylated (Supplementary Fig

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It is a 15-amino-acid pentadecapeptide derived from a protein found in human gastric juice

loading control -actin, forward sequence: 5'-CACCATTGGCAATGAGCGGTTC-3', reverse sequence: 5-AGGTCTTTGCGGAT GTCCACGT-3'