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NTZ reduced the elevation in both ALT and AST in a dose-dependent way (Figures 2A, B), whereas a significant reduction in ALP (Figure 2C) was observed with the higher dose (NTZ-200) when compared with the MTX group

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These combinations (AMY_1, AMY_2, and AMY_3 receptor subtypes) are abundantly expressed in key regions of the brain that regulate appetite and glucose metabolism particularly the area postrema and nucleus of the solitary tract in the brainstem, as well as hypothalamic nuclei involved in satiety

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Inflammation as a central mechanism in Alzheimers disease