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Vitamin B12 injections are the most common way to prevent or treat a deficiency.

The peptide reconstitution guide covers the technique in detail

For the mood and cognitive side of this, see our guides on B12 for brain health and B12 for mood and anxiety.

Self-administered B12 shots are generally recommended for individuals: whose bloodwork has documented low B12 levels Patients with pernicious anemia or a lack of intrinsic factor Individuals with Crohn's disease, celiac disease, or post-bariatric surgery malabsorption Vegans and strict vegetarians are unable to correct the deficiency through diet Older adults whose stomach acid production has declined with age Anyone on long-term metformin or proton pump inhibitors Across most of the U.S., injectable B12 is not sold over the counter a clinician has to write the script before a pharmacy can dispense it

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