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Employing the following formula prescribed for parallel trials and accounting for a 10% attrition rate in each group, the calculations indicated a need for 22 participants in each group to adequately address the research objectives

Alexis A, Moiin A, Waibel J, Wallace P, Cohen D, Laquer V, et al

Redox Biol 21:101050 TeSlaa T, Ralser M, Fan J, Rabinowitz JD (2023) The pentose phosphate pathway in health and disease

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In 2019 a multinational collaborative study of data collected in 204 countries and territories between 2000 and 2019 indicated that obesity contributed approximately 5 million deaths from major non-communicable diseases