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The association between coffee intake and the urinary concentrations of 8-hydroxydeoxyguanosine (8-OHdG), a biomarker of systemic oxidative damage and DNA repair, was analyzed: by examining more than 200 female subjects, the data showed that the urinary concentrations of 8-OHdG tended to decrease in women with a daily intake of 23 cups of coffee

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Factors That Can Reduce Glutathione Levels Several lifestyle and environmental factors can deplete glutathione levels , leading to an increased risk of oxidative stress and reduced detoxification capabilities: 1

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