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For example, azoles and dehydroalanines can be installed into peptides by chemical modification of ncAAs, which expands the chemical diversity of peptides that can be ribosomally synthesized

This "protective bubble" allows the glutathione to travel through the digestive system intact

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Over time, carnosine buffers the pH decline that causes the onset of muscle fatigue and failure, while building endurance and improving recovery

However, excessive or sustained mitochondrial damage triggers pathological overactivation of mitophagy, contributing to cell death and tissue injury (Aggarwal et al., 2016)