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Chronic obstructive pulmonary disease (COPD) including chronic bronchitis and/or emphysema were defined according to the self-reported diagnosis [9]

Several distinct populations of microglia and macrophages have been described in the aging brain, including dark microglia (Bisht et al., 2016), IFN-responsive microglia (Kaya et al., 2022), and senescent-like microglia (Gross et al., 2025), underlying the heterogeneity of immune cell responses to aging-related stress

Not recommended for individuals with known sensitivity to copper-based compounds

PMID: 11765069

After overnight culture, various concentrations of TPE-DCV were added into the 96-well plate