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Switching to a compounded formulation that includes B12 alongside the semaglutide addresses the deficiency directly, and fatigue improves by week six

Additionally, check to see if your patient is taking medications that can cause B12 deficiency

Liver disease is a significant cause of elevated B12

When administered in injectable form, vitamin B12 can: Prevent and treat myelopathy Help treat Imerslund- Grasbeck disease Treat tremors Help treat nerve damage that has resulted from shingles or diabetes Alleviate the symptoms of cyanide poisoning Help improve the symptoms of hepatitis C Treat chronic fatigue syndrome or address low energy levels Address issues with bleeding Help treat cancer Help improve the symptoms associated with liver and kidney disease Help treat psoriasis Help prevent clogged arteries after a surgical procedure

Be sure to talk about this with your doctor before starting Ozempic treatment