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The trigeminal nerve branch is another direct route from the nose to the CNS, exploited by some pathogens, such as Streptococcus agalactiae , responsible for neonatal meningitis, and Burkholderia pseudomallei , responsible for meliodosis (St

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Oxidative stress plays a significant role in regulating normal wound healing by aiding hemostasis, inflammation, wound closure, and the development and maturation of the extracellular matrix (ECM) [8]

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