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Matsumoto D, Sato K, Gonda K, Takaki Y, Shigeura T, Sato T, Aiba-Kojima E, Iizuka F, Inoue K, Suga H, Yoshimura K

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The principal manifestations of endotheliosis include degradation of the endothelial glycocalyx (thereby facilitating endothelial permeability to atherogenic lipoproteins), reduced NO bioavailability, stress-induced remodeling of receptor and secretory phenotypes, release of stress-associated miRNAs and procoagulant factors, and activation-dependent interactions with intravascular leukocytes and with the complement, hemostasis, and kallikreinkinin systems

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