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iScience 24 , 101902 (2021)

That's often serotonin, not fatigue

However, PGE2 is known to play a dual role, as it can both suppress the immune response against M.tb and protect the host from excessive inflammation, suggesting that NSAIDs should be exercised with caution for TB treatment [128]

As a former nurse, I have given hundreds of injections of all types, at all possible injection sites, for innumerous reasons and with differing patient tolerances