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Johns wort induces CYP3A4 and P-glycoprotein (P-pg), which lowers the plasma concentration of taxanes or tamoxifen and may decrease efficacy

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Benefits Supports Positive Mood : DHEA activates Sigma-1 receptors, producing mood-enhancing effects that support overall quality of life

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There are a few specific precautions to keep in mind: Long-term use: Some studies suggest that very high doses of glutathione taken over a long period could potentially lower zinc levels