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Furthermore, we observed that the expression of multiple NRF2 target genes responsible for maintaining cellular redox balance (for example, NQO1 , PRDX1 , OGGIN1 , HMOX1 , KEAP1 and SLC3A2 ) increased following mut-p53 knockdown and decreased with mut-p53 overexpression (Supplementary Fig

Although the patients urine output was normal, they had significant fluid overload with edema and accompanying respiratory distress

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These compounds are not approved by the U.S Food and Drug Administration (FDA) for weight loss, but healthcare providers prescribe these compounds off-label for weight loss and improving metabolic health

As a hallmark of this development model, large-scale gated residential communities face critical challenges related to spatial characteristics, functionality, environmental impact, social interaction, and urban identity, highlighting the urgent need for innovative reform (International Panel on Social Progress, 2018)